Leo was diagnosed with AML when he was 2.5 years old. At that time, Leo was an active boy who loved dinosaurs and visiting the zoo. After 3 unsuccessful rounds of chemotherapy, Leo underwent a cord blood transplant and finally reached remission. After 20 amazing months of remission and no complications from the transplant, Leo's leukemia returned. Leo entered 3 experimental study protocols and additionally underwent 6 more rounds of chemotherapy without reaching remission. Leo lived a little over 1 year with refractory leukemia. During this time despite the long hospitalizations and treatments, Leo continued to make the best of each day. Leo was a fighter until the very end. Leo was a courageous little lion who lived each day to the fullest. He never let his illness get him down and he never asked why me. Leo's last year was filled with joyful days and included lots of video games and smiles! Leo is an inspiration to his two little brothers - Luca and Liam.